[HTML][HTML] Circular RNAs in osteoarthritis: indispensable regulators and novel strategies in clinical implications

W Zhang, L Qi, R Chen, J He… - Arthritis …, 2021 - arthritis-research.biomedcentral.com
… Spliceosome at the 5′ donor site attacking the 3′ acceptor … by the cell surface pattern-recognition
receptors (PRRs) can … Investigation of the OA synovium immune cell indicated that …

[HTML][HTML] Intestinal anti-tissue transglutaminase2 autoantibodies: pathogenic and clinical implications for celiac disease

M Maglio, R Troncone - Frontiers in Nutrition, 2020 - frontiersin.org
… However, plasma cell function is not restricted to the production of antibodies. In fact, these
cells appear to have a functional B cell receptor (BCR), together with expression of MHCII, as …

[HTML][HTML] Biogenesis, functions, and clinical implications of circular RNAs in non-small cell lung cancer

Y Liu, X Ao, W Yu, Y Zhang, J Wang - Molecular Therapy-Nucleic Acids, 2022 - cell.com
… Moreover, we highlight their clinical implications in NSCLC treatment. … According to its
pathological features, LC is usually classified into two subtypes: small cell LC and non-small cell

[HTML][HTML] The functional roles, cross-talk and clinical implications of m6A modification and circRNA in hepatocellular carcinoma

S Qin, Y Mao, X Chen, J Xiao, Y Qin… - International Journal of …, 2021 - ncbi.nlm.nih.gov
… multiple functions in a variety of cellular processes. Although the … , their cross-talk, and clinical
implications have not been fully … donor site to the upstream splice acceptor site and forms a …

The role of non-coding RNAs in ABC transporters regulation and their clinical implications of multidrug resistance in cancer

Y Wang, Y Wang, Z Qin, S Cai, L Yu… - Expert Opinion on …, 2021 - Taylor & Francis
… been revealed, including disturbance of diverse cell signaling involved in cells apoptosis, …
with nuclear receptors [Citation5], post-translational modification as well as cell signaling …

Ischemia-reperfusion injury in marginal liver grafts and the role of hypothermic machine perfusion: molecular mechanisms and clinical implications

Z Czigany, I Lurje, M Schmelzle, W Schöning… - Journal of Clinical …, 2020 - mdpi.com
cell metabolism and reduce the oxygen demand of the allograft. However, the cellular
of the CoQ pool or flavin mononucleotide (acceptor of electrons from NADH), decrease the …

Cellular effects and clinical implications of SLC2A3 copy number variation

GC Ziegler, P Almos, RV McNeill… - Journal of Cellular …, 2020 - Wiley Online Library
… In cancer cells, GLUT3 overexpression contributes to the Warburg effect by answering the
cell's increased glycolytic demands. The SLC2A3 gene locus at chromosome 12p13.31 is …

The Yin and Yang-Like Clinical Implications of the CDKN2A/ARF/CDKN2B Gene Cluster in Acute Lymphoblastic Leukemia

C González-Gil, J Ribera, JM Ribera, E Genescà - Genes, 2021 - mdpi.com
… -cell acute lymphoblastic leukemia (T-ALL) and account for roughly 30% of copy number
alterations found in B-cell-… CDKN2A exon two at the same acceptor site but in a different reading …

HDL abnormalities in type 2 diabetes: Clinical implications

AJ Martagon, R Zubirán, R González-Arellanes… - Atherosclerosis, 2023 - Elsevier
… Furthermore, HDLs interacts with several membrane receptors (ie, the scavenger receptor
… of cell 3[H], 14[C])-cholesterol or BODIPY-Cholesterol that appears in an acceptor per unit …

Membrane-initiated estrogen, androgen, and progesterone receptor signaling in health and disease

F Mauvais-Jarvis, CA Lange, ER Levin - Endocrine reviews, 2022 - academic.oup.com
… We also highlight potential clinical implications of pathway-… the cell membrane, binding to
a specific cytoplasmic receptor, … of the steroid-receptor complex to specific “acceptor sites” on …